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Vincenzo De Sanctis Selected Research

Glucose (Dextrose)

1/2024Can we Predict Incipient Diabetes Mellitus in Patients with Transfusion Dependent β-Thalassemia (β-TDT) Referred with a History of Prediabetes?
12/2023A retrospective study of glucose homeostasis, insulin secretion, sensitivity/resistance in non- transfusion-dependent β-thalassemia patients (NTD- β Thal): reduced β-cell secretion rather than insulin resistance seems to be the dominant defect for glucose dysregulation (GD).
12/2023A prospective guide for clinical implementation of selected OGTT- derived surrogate indices for the evaluation of β- cell function and insulin sensitivity in patients with transfusion-dependent β- thalassaemia.
10/2023The effects of excess weight on glucose homeostasis in young adult females with β-thalassemia major (β-TM): a preliminary retrospective study.
1/2023Recent advancements in glucose dysregulation and pharmacological management of osteoporosis in transfusion-dependent thalassemia (TDT): an update of ICET-A (International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescence Medicine).
1/2023Longitudinal study of ICET-A on glucose tolerance, insulin sensitivity and β-cell secretion in eleven β-thalassemia major patients with mild iron overload.
1/2023Assessment of glucose homeostasis in young adult female β-thalassemia major patients (β-TM) with acquired hypogonadotropic hypogonadism (AHH) never treated with sex steroids compared to eugonadal β-TM patients with spontaneous menstrual cycles.
1/2023Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH).
12/2022Insulin-Like Growth Factor -1 (IGF-1) and Glucose Dysregulation in Young Adult Patients with β-Thalassemia Major: Causality or Potential Link?
11/2022The The use of oral glucose-lowering agents (GLAs) in β-thalassemia patients with diabetes: Preliminary data from a retrospective study of ICET-A Network.
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Vincenzo De Sanctis Research Topics

Disease

42beta-Thalassemia (Cooley's Anemia)
10/2023 - 09/2003
38Iron Overload
12/2023 - 10/2003
27Thalassemia
12/2023 - 11/2006
19Hypogonadism (Hypergonadotropic Hypogonadism)
01/2023 - 10/2008
18Hypothyroidism
01/2023 - 12/2004
13Insulin Resistance
01/2024 - 12/2004
12Infections
11/2022 - 12/2004
10Diabetes Mellitus
01/2023 - 10/2008
10Anemia
01/2022 - 10/2008
9Hypoparathyroidism
01/2018 - 12/2004
8Glucose Intolerance
12/2023 - 12/2004
8Osteoporosis
01/2023 - 09/2013
7Sickle Cell Anemia (Hemoglobin S Disease)
01/2022 - 11/2013
7Liver Diseases (Liver Disease)
01/2021 - 12/2004
6Type 2 Diabetes Mellitus (MODY)
12/2023 - 12/2004
5Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2023 - 12/2004
5Weight Gain
10/2022 - 01/2019
4COVID-19
01/2022 - 01/2020
4Fibrosis (Cirrhosis)
11/2020 - 12/2004
4Adrenal Insufficiency (Adrenal Gland Hypofunction)
01/2018 - 03/2011
3Prediabetic State (Prediabetes)
01/2024 - 01/2021
3Obesity
12/2023 - 10/2022
3Neoplasms (Cancer)
12/2023 - 02/2014
3Iron-Deficiency Anemia (Anemia, Iron Deficiency)
11/2022 - 05/2014
3Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
10/2022 - 02/2014
3Hemoglobinopathies
01/2022 - 06/2020
3Dysmenorrhea (Menstrual Pain)
01/2020 - 12/2015
3Precocious Puberty
01/2019 - 05/2006
3Vitamin D Deficiency
01/2019 - 10/2008
3Cardiomyopathies (Cardiomyopathy)
01/2018 - 10/2008
3Inborn Genetic Diseases (Disease, Hereditary)
01/2017 - 08/2012
3Hemolytic Anemia
01/2017 - 05/2008
3Bone Resorption
12/2012 - 11/2006
2Respiratory Tract Infections (Respiratory Tract Infection)
11/2022 - 11/2021
2Hypertension (High Blood Pressure)
10/2022 - 01/2015
2Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2022 - 10/2022
2Pituitary Diseases (Disease, Anterior Pituitary)
11/2021 - 03/2015
2Hyperglycemia
01/2021 - 01/2019
2Hematologic Neoplasms (Hematological Malignancy)
01/2021 - 01/2018
2Chronic Disease (Chronic Diseases)
01/2020 - 12/2014
2Pain (Aches)
01/2019 - 01/2018
2Celiac Disease (Celiac Sprue)
01/2019 - 01/2018
2Bone Diseases (Bone Disease)
01/2018 - 01/2014
2Hypercalciuria
01/2018 - 06/2010
2Hypocalcemia
01/2018 - 01/2018
2Vomiting
01/2018 - 01/2017
2Seizures (Absence Seizure)
01/2017 - 03/2011
2Gynecomastia
01/2017 - 12/2004

Drug/Important Bio-Agent (IBA)

37Glucose (Dextrose)FDA LinkGeneric
01/2024 - 12/2004
37IronIBA
12/2023 - 05/2008
19Ferritins (Ferritin)IBA
01/2024 - 10/2008
17Insulin (Novolin)FDA Link
01/2024 - 09/2012
11Insulin-Like Growth Factor I (IGF-1)IBA
01/2023 - 11/2006
10Growth Hormone (Somatotropin)IBA
01/2021 - 12/2004
8CalciumIBA
09/2018 - 06/2010
6Hydrocortisone (Cortisol)FDA LinkGeneric
12/2021 - 03/2011
6Thyroxine (Levothyroxine)FDA LinkGeneric
01/2019 - 10/2008
5Parathyroid Hormone (Parathormone)IBA
01/2018 - 11/2006
4Hemoglobins (Hemoglobin)IBA
01/2022 - 05/2008
4Adrenocorticotropic Hormone (ACTH)FDA Link
12/2021 - 11/2013
4Blood Glucose (Blood Sugar)IBA
01/2021 - 01/2018
4Hydroxyurea (Hydrea)FDA LinkGeneric
01/2021 - 12/2004
4Testosterone (Sustanon)FDA Link
01/2019 - 11/2013
4DeferiproneIBA
10/2008 - 09/2003
3Gonadotropin-Releasing Hormone (GnRH)FDA Link
12/2023 - 01/2016
36-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
12/2023 - 09/2015
3Estrogens (Estrogen)FDA Link
01/2023 - 05/2006
3Thyroid HormonesIBA
11/2021 - 10/2008
3GonadotropinsIBA
01/2019 - 05/2006
3DeferasiroxFDA Link
01/2018 - 03/2011
3Chelating AgentsIBA
11/2015 - 10/2008
3Vitamin DFDA LinkGeneric
03/2015 - 03/2011
3Follicle Stimulating Hormone (Follitropin)FDA Link
11/2014 - 11/2013
3Deferoxamine (Desferal)FDA LinkGeneric
10/2008 - 10/2003
2SteroidsIBA
01/2023 - 10/2022
2DenosumabFDA Link
01/2023 - 07/2014
2Diphosphonates (Bisphosphonates)IBA
01/2023 - 12/2013
2AndrogensIBA
01/2023 - 01/2017
2Anti-Bacterial Agents (Antibiotics)IBA
11/2022 - 01/2020
2Prednisone (Sone)FDA LinkGeneric
10/2022 - 01/2019
2CholesterolIBA
10/2022 - 01/2019
2fibrin fragment D (D-dimer)IBA
01/2022 - 11/2020
2Alanine Transaminase (SGPT)IBA
01/2022 - 07/2002
2Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
11/2021 - 11/2013
2Biomarkers (Surrogate Marker)IBA
01/2021 - 11/2006
2Oxygen (Dioxygen)IBA
11/2020 - 11/2020
2Indicators and Reagents (Reagents)IBA
01/2019 - 12/2015
2AntibodiesIBA
01/2019 - 01/2018
2Oral ContraceptivesIBA
01/2019 - 12/2015
2MineralsIBA
09/2018 - 01/2018
2EnzymesIBA
01/2018 - 01/2017
2Free RadicalsIBA
01/2018 - 03/2011

Therapy/Procedure

30Chelation Therapy (Therapy, Chelation)
01/2023 - 12/2004
27Therapeutics
11/2022 - 12/2004
19Blood Transfusion (Blood Transfusions)
01/2023 - 10/2008
6Hormone Replacement Therapy (Therapy, Hormone Replacement)
01/2023 - 03/2011
5Splenectomy
01/2023 - 10/2008
5Glycemic Control
01/2023 - 12/2004
3Aftercare (After-Treatment)
01/2020 - 03/2011
2Drug Therapy (Chemotherapy)
01/2018 - 10/2003